Transforming Cancer Diagnostics with Liquid Biopsy
GBC’s CellBio™ platforms and CTC detection reagents deliver automated, non-invasive solutions for early cancer detection, treatment monitoring, pathology, and precision oncology.
By capturing and analyzing circulating tumor cells (CTCs) from blood samples, we enable molecular insights that improve diagnostic accuracy and drive personalized therapies.
Highlights:
- Non-invasive screening for early cancer detection
- Real-time monitoring of treatment response
- Pathology integration for deeper diagnostic insights
- Precision oncology supporting targeted therapies
Technology
CellBio™ Technology
GBC CellBio™ is an automated liquid biopsy platform that captures and harvests circulating tumor cells (CTCs) — and other rare/abnormal cells — from a standard blood draw for clinical research and translational applications. Because collection is non-invasive and repeatable, CellBio™ enables longitudinal, real-time insights into tumor biology for screening, therapy monitoring, and precision care.
Unlike ctDNA tests, which are limited to nucleic acids, intact CTCs preserve cellular morphology and multi-omic signals (DNA/RNA/protein), supporting cytology, immunostaining, and molecular profiling on the same sample to inform oncology and pathology workflows.
What are CTCs?
Circulating tumor cells are rare cancer cells that leave the primary tumor and enter the bloodstream. Studying CTCs can reveal tumor burden, phenotype (epithelial/mesenchymal), and molecular changes associated with progression and treatment response.
How it works?
CellBio™ uses a microfluidic, size/deformability-based capture approach to enrich intact CTCs directly from whole blood, then harvests them for downstream assays (e.g., immunostaining, FISH, qPCR, NGS, cell culture). This marker-independent workflow supports diverse CTC phenotypes and reduces hands-on steps, streamlining rare-cell analysis.
Step 1:
Collect a 10ml EDTA blood sample from the patient
Step 2:
Insert the sample tube into the GB CellBio™ a2000 with the iFiltration™ box installed. No pre-treatment is required.
Step 3:
Press the button, and the system will automatically pass the blood through the iFiltration™ box.
Step 4 :
The iFiltration™ box will stain with the selected antibodies or Wright’s stain. CTCs or abnormal cells on the iFiltration™ box will be counted under a fluorescence microscope.
Advantages
CTCs, Rare Cells, and More — Powered by CellBio™
CellBio™ delivers an automated, lab-friendly workflow to capture intact CTCs and other rare cells without complex pre-processing, supporting fast turnaround and reliable results for oncology and pathology teams.
Key benefits:
- Fast, streamlined workflow — non-invasive blood sample in; enriched cells out; minimal hands-on time
- Marker-independent capture — supports epithelial, mesenchymal, and clustered CTCs
- Intact cells for multi-omics — perform morphology + IF/IHC + FISH + qPCR + NGS + culture on the same sample
- Quality built-in — checkpoints and standardized reagents help ensure run-to-run consistency
- Scalable throughput — flexible configurations for small batches or higher-volume runs
System capacity:
- CellBio™ a2000 — up to 2 samples per run
- CellBio™ FX10 — up to 10 samples per run
CellBio™ Dx Reagent Kit
Designed to complement the CellBio™ workflow:
- iFiltration™ Unit
- Prefixation Buffer
- Positive Control
- Fixation/Permeabilization Buffer
- Mounting Solution with DAPI
- Staining Solution
- Concentrated Washing Solution (20×)
Service by Laboratory
myCTmyCTC Laboratory Services (Danner & CurieMed)
Purpose-built CTC analysis without building your own lab Powered by GBC CellBio™, our myCTC service provides end-to-end rare-cell analysis from a standard blood draw. Ideal for biopharma, CROs, hospital pathology labs, and academic centers, we support both clinical research and translational studies
What We Do
- CTC and cluster detection and enumeration
Detection and counting of epithelial, mesenchymal, and carcinoma-type CTCs, as well as CTC clusters with morphology-based review. - Phenotyping and imaging
High-quality microscopy with immunofluorescence or IHC panels, providing curated image sets for deeper insights. - Molecular analysis
Flexible downstream workflows including FISH, qPCR/RT-qPCR, and NGS for DNA/RNA profiling. - Custom research services
Study-specific method development, assay optimization, and protocol customization. We also support companion diagnostics and exploratory biomarker studies.
How It Works
- Project scoping – Define study goals, markers, and analytical endpoints including enumeration, IF/IHC, FISH, qPCR, or NGS.
- Collection and logistics – Provide validated blood collection kits and SOPs to ensure sample integrity during transit.
- CellBio™ enrichment – Automated, marker-independent capture of intact CTCs suitable for both cytology and multi-omics.
- Analysis and reporting – Deliver standardized reports including CTC counts, images, QC metrics, and assay methods. Optional raw data packages are available.
- Review and optimization – Optional consultation with our scientists to refine protocols or scale up for multi-site studies.
What You Receive
- Comprehensive study report including counts, representative images, assay methods, and QC metrics
- Optional data package including images, processed results, and raw genomics data for deeper analysis
- Operational flexibility to support pilot studies, larger clinical programs, or technology transfer for partner labs
Regulatory note: Services are provided for research use only (RUO) unless otherwise specified.
Collaboration Opportunities
We collaborate with biopharma companies, CROs, insurers, biotech innovators, and clinical laboratories to unlock rare-cell insights and co-develop advanced diagnostic strategies.
[CONTACT US] to discuss your project.
Application
GB CellBio™ Technology can be used in various cell types and flexible downstream Molecular Analysis:
1) Cell Types:
- Cancer Cells
- Stem Cells
- Cell Clusters
- Fetal Cells
- PBMCs
2) Downstream Molecular Analysis:
- FISH
- IHC
- qPCR
- NGS
- Enumeration
- Cell Culture
PRODUCTS
LET’S CONNECT
Discover how GBC’s experts can support your next complex diagnostic project