Transforming Cancer Diagnostics with Liquid Biopsy
GBC CellBio™ is built around circulating tumor cell (CTC) and rare-cell analysis, integrating automated cell enrichment, isolation and downstream analysis to support liquid biopsy, pathology research and precision oncology applications.
By preserving intact cellular morphology and biological information, CellBio™ enables downstream analysis including morphology, immunostaining, FISH, qPCR and NGS, providing richer cellular insights for clinical and translational research.
Key Highlights
- Non-invasive blood sampling — CTC and rare-cell analysis from blood samples
- Intact-cell capture — Preserves cellular morphology and information for downstream analysis
- Multi-modal analysis — Supports morphology, IF/IHC, FISH, qPCR, NGS and other analytical methods
Technology
CellBio™ Technology
GBC CellBio™ is an automated CTC and rare-cell enrichment platform designed to capture, enrich and recover intact CTCs and other rare cells directly from standard blood samples for downstream morphology, imaging, biomarker and molecular analysis.
Using marker-independent cell enrichment technology, CellBio™ preserves intact cellular morphology and biological information, enabling the same research sample to support morphology, immunostaining, FISH and molecular analysis for tumor biology, biomarker and translational research.
What Are CTCs?
Circulating tumor cells (CTCs) are rare cells shed from tumors into the bloodstream. CTC analysis enables researchers to study cell counts, morphology, phenotype and related molecular characteristics, providing valuable information for tumor biology and translational research.
How It works?
CellBio™ uses a microfluidic, size/deformability-based capture approach to enrich intact CTCs directly from whole blood, then harvests them for downstream assays (e.g., immunostaining, FISH, qPCR, NGS, cell culture). This marker-independent workflow supports diverse CTC phenotypes and reduces hands-on steps, streamlining rare-cell analysis.
Step 1:
Collect a 10 mL EDTA whole-blood sample.
Step 2:
Load the sample and iFiltration™ unit into the CellBio™ system. No pre-treatment required.
Step 3:
Marker-independent enrichment based on physical cell characteristics.
Step 4 :
Perform morphology, staining, imaging or molecular analysis.
Advantages
Advancing CTC & Rare-Cell Analysis with CellBio™
Marker-Independent Capture
Supports research across different CTC phenotypes and rare-cell populations without relying on a single surface marker.
Intact-Cell Recovery
Preserves intact cells for morphology and downstream molecular analysis.
Multi-Modal Analysis
Supports IF/IHC, FISH, qPCR, NGS and other analytical methods.
Scalable Automation
CellBio™ a2000 supports up to 2 samples per run; FX10 supports up to 10 samples per batch.
myCTC™ Laboratory Services
Powered by the GBC CellBio™ automated CTC and rare-cell enrichment platform, myCTC™ enriches and preserves intact CTCs and rare cells from blood samples and integrates cellular morphology, imaging, biomarker, FISH and molecular analysis. The service supports biopharma companies, CROs, healthcare institutions and research teams with integrated workflows from sample to research data.
One Blood Sample. Multiple Layers of Insight.
| 01 |
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02 |
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03 |
| See the Cells | Characterize the Cells | Explore Molecular Features |
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Cell Morphology Cell Imaging CTC / CTC Clusters |
IF / IHC Protein Biomarkers FISH |
qPCR / RT-qPCR NGS DNA / RNA |
Integrated CTC & Biomarker Analysis Services
01 — CTC & Rare-Cell Profiling
CTC and CTC-cluster enrichment, detection, enumeration, morphology and imaging.
02 — Protein & Biomarker Analysis
IF/IHC-based cellular phenotyping and target biomarker analysis.
03 — FISH & Molecular Profiling
FISH, RT-qPCR and NGS analysis for chromosomal, DNA and RNA features.
04 — Custom Biomarker Development
Feasibility assessment, assay development and optimization, and customized research workflows.
From Feasibility Studies to Scalable Collaboration
myCTC™ supports flexible collaboration across different stages of research, from early feasibility assessment and pilot studies to biomarker method development, translational research and larger-scale research programs.
For partners seeking to establish in-house CTC and rare-cell analysis capabilities, CellBio™ platform implementation and technology transfer can also be explored.
Collaboration Partners
Biopharma · CROs · Healthcare Institutions · Clinical Laboratories · Academic & Research Teams
Research Use Only (RUO)
Unless otherwise specified, myCTC™ services are intended for research use only.
CellBio™ & myCTC™ Research Applications
CellBio™ and myCTC™ support a range of CTC, rare-cell and biomarker research applications, combining intact-cell analysis with downstream cellular and molecular methods.
Biomarker Discovery
Explore cellular, protein and molecular biomarkers using enriched CTCs and rare cells.
Drug Development Research
Support exploratory biomarker studies and CTC-based research across drug development programs.
Pharmacodynamic & Biomarker Research
Investigate cellular and molecular biomarker changes in research studies.
Treatment Resistance Research
Explore cellular and molecular characteristics associated with treatment resistance.
Longitudinal Biomarker Research
Study changes in CTCs and related biomarkers across multiple time points.
Translational Research
Connect cellular, pathology, biomarker and molecular findings to support translational oncology research.
PRODUCTS
Compact Benchtop CTC Enrichment System GBC CellBio™ a2000 is a compact, semi-automated circulating tumor cell (CTC) enrichment system powered by patented iFiltration™ technology. Designed for liquid biopsy research, it enriches intact CTCs and rare cells from whole blood for downstream cellular and molecular analysis. With a capacity of up to two samples per run, CellBio a2000 offers a practical solution for research laboratories establishing CTC enrichment capabilities.
High-Throughput Automated CTC Enrichment System GBC CellBio FX10 is a high-throughput, fully automated circulating tumor cell (CTC) enrichment system powered by patented iFiltration™ technology. Designed for liquid biopsy research, it enriches intact CTCs and rare cells from whole blood for downstream cellular and molecular analysis. With a capacity of up to 10 samples per run and 40 samples per day, CellBio FX10 supports laboratories requiring higher-throughput CTC enrichment workflows.
CTC Enrichment and Fluorescent Staining Kit GB iFiltration™ CTC Kit is a circulating tumor cell (CTC) enrichment and fluorescent staining kit featuring patented high-density microporous filtration technology. Designed for liquid biopsy research, it enriches intact CTCs and rare cells from 7.5 mL of whole blood and supports fluorescence-based cell analysis using CK, EpCAM, CD45, and DAPI markers. Each kit provides 10 tests.
Collaborate with GBC on CTC & Biomarker Research
GBC supports CTC, rare-cell and biomarker research through myCTC™ services and CellBio™ platforms.